---
author: "Umesh Malik"
canonical: "https://umesh-malik.com/blog/tag/connectome"
description: "Explore articles tagged with Connectome by Umesh Malik — AI Engineer, LLM & GenAI Developer. Learn Connectome best practices, practical tips, and in-depth guides."
title: "Umesh Malik's Blog - Connectome Articles | Connectome Tutorials"
tokens: 153
generator: "scripts/generate-page-markdown.mjs"
---

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# Connectome

1 article

 [![Three brain-wiring strategies compared by information cost, from an infeasible 3x10^15 bits down to a genome-feasible 300 million bits](https://umesh-malik.com/blog/how-dna-wires-a-brain-cover.png)

AI Engineering • Aug 16, 2026

### How DNA wires a brain: 300M bits for 100 trillion connections

How DNA wires a brain: a ~10B-bit genome must wire 100 trillion connections. The scheme that closes the gap in 300M bits, and why two simpler plans fail first.

9 min read

Read more →](https://umesh-malik.com/blog/how-dna-wires-a-brain)